#1-PRESCRIBED BRAND HYDROCODONE ANTITUSSIVE PROVIDES UP TO 12 HOUR COUGH RELIEF WITH 1 DOSE1

TUSSIONEX®: The most prescribed hydrocodone antitussive

  • 2 out of 3 prescriptions for a hydrocodone antitussive are written for TUSSIONEX®1

Innovative Pennkinetic® delivery system provides consistent plasma levels for up to 12 hours2

  • May reduce sleep interruptions, which may occur with need to re-dose short-acting antitussives
  • Nationwide availability

TUSSIONEX® is contraindicated in children under the age of 6 years of age due to the risk of fatal respiratory depression, and in the presence of known allergy or sensitivity to hydrocodone or chlorpheniramine.

Important Safety Information

Learn more about TUSSIONEX®:

Dosing Instructions2

Overdose with TUSSIONEX® has been associated with fatal respiratory depression. Patients should be advised to measure TUSSIONEX® with an accurate measuring device. A household teaspoon is not an accurate measuring device. As with any other drugs in this class, the possibility of tolerance and/or dependence, particularly in patients with a history of drug dependence, should be considered.

IMPORTANT SAFETY INFORMATION

  • TUSSIONEX® is contraindicated in children less than 6 years of age due to the risk of fatal depression, and in patients with a known allergy or sensitivity to hydrocodone or chlorpheniramine.
  • TUSSIONEX® may produce dose-related respiratory depression or irregular and periodic breathing. Caution should be exercised when TUSSIONEX is used postoperatively and in patients with pulmonary disease, or whenever ventilatory function is depressed.
  • The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, other intracranial lesions, or a pre-existing increase in intracranial pressure. Furthermore, narcotics produce adverse reactions, which may obscure the clinical course of patients with head injuries.
  • TUSSIONEX® is a Schedule III narcotic. Psychic dependence, physical dependence and tolerance may develop upon repeated administration of narcotics; therefore, TUSSIONEX Pennkinetic Extended-Release Suspension should be prescribed and administered with caution.
  • The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions.
  • Chronic use of narcotics may result in obstructive bowel disease especially in patients with underlying intestinal motility disorder.
  • Caution is advised when prescribing this drug to patients with narrow-angle glaucoma, asthma, or prostatic hypertrophy.
  • TUSSIONEX® should be used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture.
  • Hydrocodone suppresses the cough reflex; caution should be exercised when TUSSIONEX® is used postoperatively, and in patients with pulmonary disease.
Indication

TUSSIONEX® is indicated for relief of cough and upper respiratory symptoms associated with allergy or a cold in adults and children 6 years of age and older.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

References:
1. IMS Health, Inc. National Prescription Audit, 2010.

TUSSIONEX®, PENNKINETIC®, and COUGH RELIEVED. REST ASSURED.™ are trademarks of the UCB Group of companies. All other trademarks are owned by their respective trademark holders.